It is a challenge to keep abreast of all the clinical and scientific advances in the field of respiratory medicine.This article contains an overview of the laboratory-based science, clinical trials and qualitative research that were presented during the 2022 pentair hose European Respiratory Society International Congress within the sessions from the five groups of Assembly 1 (Respiratory Clinical Care and Physiology).Selected presentations are summarised from a wide range of topics: clinical problems, rehabilitation and chronic care, general practice and primary care, mobile/electronic health alarecre.com (m-health/e-health), clinical respiratory physiology, exercise and functional imaging.